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The Effect of Biorelevant Hydrodynamic Conditions on Drug Dissolution from Extended-Release Tablets in the Dynamic Colon Model

The in vitro release of theophylline from an extended-release dosage form was studied under different hydrodynamic conditions in a United States Pharmacopoeial (USP) dissolution system II and a bespoke in vitro tubular model of the human colon, the Dynamic Colon Model (DCM). Five biorelevant motilit...

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Detalles Bibliográficos
Autores principales:	O’Farrell, Connor, Simmons, Mark J. H., Batchelor, Hannah K., Stamatopoulos, Konstantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609852/ https://www.ncbi.nlm.nih.gov/pubmed/36297627 http://dx.doi.org/10.3390/pharmaceutics14102193

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