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Antihypertensive Activity of the Alkaloid Aspidocarpine in Normotensive Wistar Rats

The alkaloid Aspidocarpine was isolated from the bark of Aspidosperma desmanthum. Its structure was elucidated by the spectral data of (1)H and (13)C-NMR (1D and 2D) and high-resolution mass spectrometry (HRESIMS). The antihypertensive activity was investigated by intravenous infusion in Wistar rats...

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Detalles Bibliográficos
Autores principales: Monteiro, Noemi Oliveira, Monteiro, Theresa de Moura, Nogueira, Thalya Soares R., Cesar, Jacqueline Rodrigues, Nascimento, Lara Pessanha S., Campelo, Karoline Azerêdo, Silveira, Graziela Rangel, Antunes, Fernanda, de Oliveira, Daniela Barros, de Carvalho Junior, Almir Ribeiro, Braz-Filho, Raimundo, Vieira, Ivo José Curcino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609921/
https://www.ncbi.nlm.nih.gov/pubmed/36296487
http://dx.doi.org/10.3390/molecules27206895