In Vitro Characterization of Inhibitors for Lung A549 and Leukemia K562 Cell Lines from Fungal Transformation of Arecoline Supported by In Silico Docking to M3-mAChR and ADME Prediction

The search for anticancer drugs is of continuous interest. Arecoline is an alkaloid with anticancer activity. Herein, the metabolism of arecoline through fungal transformation was investigated for the discovery of potential anticancer drugs with higher activity and selectivity. Compounds 1–5 were is...

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Detalles Bibliográficos
Autores principales: Ragab, Amany E., Badawy, Ebtisam T., Aboukhatwa, Shaimaa M., Kabbash, Amal, Abo El-Seoud, Kamilia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609924/
https://www.ncbi.nlm.nih.gov/pubmed/36297282
http://dx.doi.org/10.3390/ph15101171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609924/
https://www.ncbi.nlm.nih.gov/pubmed/36297282
http://dx.doi.org/10.3390/ph15101171

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