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Benzimidazole Bearing Thiosemicarbazone Derivatives Act as Potent α-Amylase and α-Glucosidase Inhibitors; Synthesis, Bioactivity Screening and Molecular Docking Study

Diabetes mellitus is one of the most chronic metabolic diseases. In the past few years, our research group has synthesized and evaluated libraries of heterocyclic analogs against α-glucosidase and α-amylase enzymes and found encouraging results. The current study comprises the evaluation of benzimid...

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Detalles Bibliográficos
Autores principales: Ullah, Hayat, Khan, Shoaib, Rahim, Fazal, Taha, Muhammad, Iqbal, Rashid, Sarfraz, Maliha, Shah, Syed Adnan Ali, Sajid, Muhammad, Awad, Mohamed F., Omran, Awatif, Albalawi, Marzough Aziz, Abdelaziz, Mahmoud A., Al Areefy, Azza, Jafri, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609971/
https://www.ncbi.nlm.nih.gov/pubmed/36296520
http://dx.doi.org/10.3390/molecules27206921