Assembly of Biologically Functional Structures by Nucleic Acid Templating: Implementation of a Strategy to Overcome Inhibition by Template Excess

Delivery of therapeutic molecules to pathogenic cells is often hampered by unintended toxicity to normal cells. In principle, this problem can be circumvented if the therapeutic effector molecule is split into two inactive components, and only assembled on or within the target cell itself. Such an i...

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Detalles Bibliográficos
Autores principales: Lawler, Matthew M., Kurnick, James T., Fagundes St. Pierre, Leah, Newton, Estelle E., Rose, Lenora B., Dunn, Ian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610079/
https://www.ncbi.nlm.nih.gov/pubmed/36296424
http://dx.doi.org/10.3390/molecules27206831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610079/
https://www.ncbi.nlm.nih.gov/pubmed/36296424
http://dx.doi.org/10.3390/molecules27206831

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