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Assembly of Biologically Functional Structures by Nucleic Acid Templating: Implementation of a Strategy to Overcome Inhibition by Template Excess
Delivery of therapeutic molecules to pathogenic cells is often hampered by unintended toxicity to normal cells. In principle, this problem can be circumvented if the therapeutic effector molecule is split into two inactive components, and only assembled on or within the target cell itself. Such an i...
Autores principales: | Lawler, Matthew M., Kurnick, James T., Fagundes St. Pierre, Leah, Newton, Estelle E., Rose, Lenora B., Dunn, Ian S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610079/ https://www.ncbi.nlm.nih.gov/pubmed/36296424 http://dx.doi.org/10.3390/molecules27206831 |
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