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Genotyping of UGT1A1*80 as an Alternative to UGT1A1*28 Genotyping in Spain

Background: The variant rs34983651 (UGT1A1*28) and its genotyping are used to prevent irinotecan-induced toxicity. Several variants are in close linkage disequilibrium. Our objective was to evaluate the potential correlation of genotyping UGT1A1*80 instead of UGT1A1*28 in different populations. Meth...

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Detalles Bibliográficos
Autores principales: Bravo-Gómez, Adrián, Salvador-Martín, Sara, Zapata-Cobo, Paula, Sanjurjo-Sáez, María, López-Fernández, Luis Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610287/
https://www.ncbi.nlm.nih.gov/pubmed/36297516
http://dx.doi.org/10.3390/pharmaceutics14102082