Evolution of naturally arising SARS-CoV-2 defective interfering particles

Defective interfering (DI) particles arise during virus propagation, are conditional on parental virus for replication and packaging, and interfere with viral expansion. There is much interest in developing DIs as anti-viral agents. Here we characterize DI particles that arose following serial passa...

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Detalles Bibliográficos
Autores principales: Girgis, Samer, Xu, Zaikun, Oikonomopoulos, Spyros, Fedorova, Alla D., Tchesnokov, Egor P., Gordon, Calvin J., Schmeing, T. Martin, Götte, Matthias, Sonenberg, Nahum, Baranov, Pavel V., Ragoussis, Jiannis, Hobman, Tom C., Pelletier, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610340/
https://www.ncbi.nlm.nih.gov/pubmed/36302891
http://dx.doi.org/10.1038/s42003-022-04058-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610340/
https://www.ncbi.nlm.nih.gov/pubmed/36302891
http://dx.doi.org/10.1038/s42003-022-04058-5

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