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Discovery of 2′,6-Bis(4-hydroxybenzyl)-2-acetylcyclohexanone, a Novel FtsZ Inhibitor

Multi-drug resistance is increasing in the pathogenic bacterium S. pneumoniae, which is mainly responsible for meningitis and community-acquired pneumonia (CAP), highlighting the need for new anti-pneumococcal agents. We have identified a potential anti-pneumococcal agent, enol 3, which acts by hind...

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Detalles Bibliográficos
Autores principales: Lin, Hsuan-Yu J., Battaje, Rachana Rao, Tan, Jinlong, Doddareddy, Munikumar, Dhaked, Hemendra Pal Singh, Srivastava, Shalini, Hawkins, Bryson A., Al-Shdifat, Laith Mohammad Hilal, Hibbs, David E., Panda, Dulal, Groundwater, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610434/
https://www.ncbi.nlm.nih.gov/pubmed/36296585
http://dx.doi.org/10.3390/molecules27206993