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BRD9 Inhibition by Natural Polyphenols Targets DNA Damage/Repair and Apoptosis in Human Colon Cancer Cells

Epigenetic mechanisms play an important role in the etiology of colorectal cancer (CRC) and other malignancies due, in part, to deregulated bromodomain (BRD) functions. Inhibitors of the bromodomain and extraterminal (BET) family have entered into clinical trials as anticancer agents, and interest h...

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Detalles Bibliográficos
Autores principales: Kapoor, Sabeeta, Damiani, Elisabetta, Wang, Shan, Dharmanand, Ravirajan, Tripathi, Chakrapani, Tovar Perez, Jorge Enrique, Dashwood, Wan Mohaiza, Rajendran, Praveen, Dashwood, Roderick Hugh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610492/
https://www.ncbi.nlm.nih.gov/pubmed/36297001
http://dx.doi.org/10.3390/nu14204317