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Acetyl Co-A Carboxylase Inhibition Halts Hyperglycemia Induced Upregulation of De Novo Lipogenesis in Podocytes and Proximal Tubular Cells

The effect of glycemic stress on de novo lipogenesis (DNL) in podocytes and tubular epithelial cells is understudied. This study is aimed (A) to show the effect of glycemic stress on DNL, and (B) to assess the effect of acetyl-Co A (ACC) inhibition on halting upregulation of DNL, on the expression o...

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Detalles Bibliográficos
Autores principales: Kayampilly, Pradeep, Roeser, Nancy, Rajendiran, Thekkelnaycke M, Pennathur, Subramaniam, Afshinnia, Farsad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610518/
https://www.ncbi.nlm.nih.gov/pubmed/36295842
http://dx.doi.org/10.3390/metabo12100940