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Acetyl Co-A Carboxylase Inhibition Halts Hyperglycemia Induced Upregulation of De Novo Lipogenesis in Podocytes and Proximal Tubular Cells
The effect of glycemic stress on de novo lipogenesis (DNL) in podocytes and tubular epithelial cells is understudied. This study is aimed (A) to show the effect of glycemic stress on DNL, and (B) to assess the effect of acetyl-Co A (ACC) inhibition on halting upregulation of DNL, on the expression o...
Autores principales: | Kayampilly, Pradeep, Roeser, Nancy, Rajendiran, Thekkelnaycke M, Pennathur, Subramaniam, Afshinnia, Farsad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610518/ https://www.ncbi.nlm.nih.gov/pubmed/36295842 http://dx.doi.org/10.3390/metabo12100940 |
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