Identification of New L-Heptanoylphosphatidyl Inositol Pentakisphosphate Derivatives Targeting the Interaction with HIV-1 Gag by Molecular Modelling Studies

The HIV-1 Gag protein binds to the host cell membrane and assembles into immature particles. Then, in the course of immature virion budding, activated protease cleaves Gag into its main components: MA, CA, NC, and p6 proteins. The highly basic residues of MA predominantly interact with the acidic he...

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Detalles Bibliográficos
Autores principales: Ciftci, Halilibrahim, Sever, Belgin, Ayan, Esra, Can, Mustafa, DeMirci, Hasan, Otsuka, Masami, TuYuN, Amaç Fatih, Tateishi, Hiroshi, Fujita, Mikako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610595/
https://www.ncbi.nlm.nih.gov/pubmed/36297367
http://dx.doi.org/10.3390/ph15101255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610595/
https://www.ncbi.nlm.nih.gov/pubmed/36297367
http://dx.doi.org/10.3390/ph15101255

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