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Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase

In this study, a stepwise reaction afforded thiazolidinone-based benzothiazole derivatives 1–15, and the synthesized derivatives were then screened for biological significance and found to be the leading candidates against α-amylase and α-glucosidase enzymes. Almost all derivatives showed excellent...

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Detalles Bibliográficos
Autores principales: Khan, Shoaib, Iqbal, Shahid, Khan, Marwa, Rehman, Wajid, Shah, Mazloom, Hussain, Rafaqat, Rasheed, Liaqat, Khan, Yousaf, Dera, Ayed A., Pashameah, Rami Adel, Alzahrani, Eman, Farouk, Abd-ElAziem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610606/
https://www.ncbi.nlm.nih.gov/pubmed/36297276
http://dx.doi.org/10.3390/ph15101164