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Impact of HLA Polymorphism on the Immune Response to Bacillus Anthracis Protective Antigen in Vaccination versus Natural Infection

The causative agent of anthrax, Bacillus anthracis, evades the host immune response and establishes infection through the production of binary exotoxins composed of Protective Antigen (PA) and one of two subunits, lethal factor (LF) or edema factor (EF). The majority of vaccination strategies have f...

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Detalles Bibliográficos
Autores principales: Ascough, Stephanie, Ingram, Rebecca J., Chu, Karen K. Y., Moore, Stephen J., Gallagher, Theresa, Dyson, Hugh, Doganay, Mehmet, Metan, Gökhan, Ozkul, Yusuf, Baillie, Les, Williamson, E. Diane, Robinson, John H., Maillere, Bernard, Boyton, Rosemary J., Altmann, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610610/
https://www.ncbi.nlm.nih.gov/pubmed/36298436
http://dx.doi.org/10.3390/vaccines10101571