Aconitum Alkaloid Songorine Exerts Potent Gamma-Aminobutyric Acid-A Receptor Agonist Action In Vivo and Effectively Decreases Anxiety without Adverse Sedative or Psychomotor Effects in the Rat

Songorine (SON) is a diterpenoid alkaloid from Aconitum plants. Preparations of Aconitum roots have been employed in traditional oriental herbal medicine, however, their mechanisms of action are still unclear. Since GABA-receptors are possible brain targets of SON, we investigated which subtypes of...

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Detalles Bibliográficos
Autores principales: Bali, Zsolt Kristóf, Bruszt, Nóra, Kőszegi, Zsombor, Nagy, Lili Veronika, Atlasz, Tamás, Kovács, Péter, Csupor, Dezső, Csupor-Löffler, Boglárka, Hernádi, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610616/
https://www.ncbi.nlm.nih.gov/pubmed/36297502
http://dx.doi.org/10.3390/pharmaceutics14102067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610616/
https://www.ncbi.nlm.nih.gov/pubmed/36297502
http://dx.doi.org/10.3390/pharmaceutics14102067

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