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sPLA2 Wobbles on the Lipid Bilayer between Three Positions, Each Involved in the Hydrolysis Process

Secreted phospholipases A2 (sPLA2s) are peripheral membrane enzymes that hydrolyze phospholipids in the sn-2 position. The action of sPLA2 is associated with the work of two active sites. One, the interface binding site (IBS), is needed to bind the enzyme to the membrane surface. The other one, the...

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Detalles Bibliográficos
Autores principales: Kuzmina, Natalia, Volynsky, Pavel, Boldyrev, Ivan, Alekseeva, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610741/
https://www.ncbi.nlm.nih.gov/pubmed/36287938
http://dx.doi.org/10.3390/toxins14100669