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Actin-binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II
We report a case in which sub-stoichiometric binding of an actin-binding protein has profound structural and functional consequences, providing an insight into the fundamental properties of actin regulation. Rng2 is an IQGAP contained in contractile rings in the fission yeast Schizosaccharomyces pom...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610768/ https://www.ncbi.nlm.nih.gov/pubmed/36288901 http://dx.doi.org/10.26508/lsa.202201469 |