Actin-binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II

We report a case in which sub-stoichiometric binding of an actin-binding protein has profound structural and functional consequences, providing an insight into the fundamental properties of actin regulation. Rng2 is an IQGAP contained in contractile rings in the fission yeast Schizosaccharomyces pom...

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Detalles Bibliográficos
Autores principales: Hayakawa, Yuuki, Takaine, Masak, Ngo, Kien Xuan, Imai, Taiga, Yamada, Masafumi D, Behjat, Arash Badami, Umeda, Kenichi, Hirose, Keiko, Yurtsever, Ayhan, Kodera, Noriyuki, Tokuraku, Kiyotaka, Numata, Osamu, Fukuma, Takeshi, Ando, Toshio, Nakano, Kentaro, Uyeda, Taro QP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610768/
https://www.ncbi.nlm.nih.gov/pubmed/36288901
http://dx.doi.org/10.26508/lsa.202201469

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