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A Secreted Form of the Hepatitis E Virus ORF2 Protein: Design Strategy, Antigenicity and Immunogenicity

Hepatitis E virus (HEV) is an important public health burden worldwide, causing approximately 20 million infections and 70,000 deaths annually. The viral capsid protein is encoded by open reading frame 2 (ORF2) of the HEV genome. Most ORF2 protein present in body fluids is the glycosylated secreted...

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Detalles Bibliográficos
Autores principales: Chen, Zihao, Guo, Shaoqi, Li, Guanghui, Ying, Dong, Wen, Guiping, Fang, Mujin, Wang, Yingbin, Tang, Zimin, Zheng, Zizheng, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610824/
https://www.ncbi.nlm.nih.gov/pubmed/36298677
http://dx.doi.org/10.3390/v14102122