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Locust Bean Gum Nano-Based Hydrogel for Vaginal Delivery of Diphenyl Diselenide in the Treatment of Trichomoniasis: Formulation Characterization and In Vitro Biological Evaluation

Trichomoniasis is the most common nonviral sexually transmitted infection in the world, but its available therapies present low efficacy and high toxicity. Diphenyl diselenide (PhSe(2)) is a pharmacologically active organic selenium compound; however, its clinical use is hindered by its lipophilicit...

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Detalles Bibliográficos
Autores principales: dos Reis, Fernanda Padoin, Rigo, Graziela Vargas, Nogueira, Cristina Wayne, Tasca, Tiana, Sari, Marcel Henrique Marcondes, Cruz, Letícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610892/
https://www.ncbi.nlm.nih.gov/pubmed/36297547
http://dx.doi.org/10.3390/pharmaceutics14102112