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Locust Bean Gum Nano-Based Hydrogel for Vaginal Delivery of Diphenyl Diselenide in the Treatment of Trichomoniasis: Formulation Characterization and In Vitro Biological Evaluation
Trichomoniasis is the most common nonviral sexually transmitted infection in the world, but its available therapies present low efficacy and high toxicity. Diphenyl diselenide (PhSe(2)) is a pharmacologically active organic selenium compound; however, its clinical use is hindered by its lipophilicit...
Autores principales: | dos Reis, Fernanda Padoin, Rigo, Graziela Vargas, Nogueira, Cristina Wayne, Tasca, Tiana, Sari, Marcel Henrique Marcondes, Cruz, Letícia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610892/ https://www.ncbi.nlm.nih.gov/pubmed/36297547 http://dx.doi.org/10.3390/pharmaceutics14102112 |
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