Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres

Rutin, a natural flavonol, can modulate molecular signaling pathways and has considerable potential in cancer treatment. However, little is known about the effect of rutin on the notch signaling pathway (NSP) in cancer and cancer stem-like cells. In this study, we explored the effect of rutin on gam...

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Detalles Bibliográficos
Autores principales: Singh, Atul Kumar, Shuaib, Mohd, Prajapati, Kumari Sunita, Kumar, Shashank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610901/
https://www.ncbi.nlm.nih.gov/pubmed/36295828
http://dx.doi.org/10.3390/metabo12100926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610901/
https://www.ncbi.nlm.nih.gov/pubmed/36295828
http://dx.doi.org/10.3390/metabo12100926

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