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Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres
Rutin, a natural flavonol, can modulate molecular signaling pathways and has considerable potential in cancer treatment. However, little is known about the effect of rutin on the notch signaling pathway (NSP) in cancer and cancer stem-like cells. In this study, we explored the effect of rutin on gam...
Autores principales: | Singh, Atul Kumar, Shuaib, Mohd, Prajapati, Kumari Sunita, Kumar, Shashank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610901/ https://www.ncbi.nlm.nih.gov/pubmed/36295828 http://dx.doi.org/10.3390/metabo12100926 |
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