Simultaneous Analysis of a Combination of Anti-Hypertensive Drugs, Fimasartan, Amlodipine, and Hydrochlorothiazide, in Rats Using LC-MS/MS and Subsequent Application to Pharmacokinetic Drug Interaction with Red Ginseng Extract

Fimasartan, amlodipine, and hydrochlorothiazide are commonly used in combination therapies as antihypertensive drugs. This study aimed to develop and validate an analytical method for fimasartan, its active and major metabolite fimasartan-amide, amlodipine, and hydrochlorothiazide in rat plasma usin...

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Detalles Bibliográficos
Autores principales: Jeon, So-Yeon, Jeon, Ji-Hyeon, Park, Jin-Hyang, Lee, Jihoon, Pang, Minyeong, Choi, Min-Koo, Song, Im-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610909/
https://www.ncbi.nlm.nih.gov/pubmed/36287856
http://dx.doi.org/10.3390/toxics10100576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610909/
https://www.ncbi.nlm.nih.gov/pubmed/36287856
http://dx.doi.org/10.3390/toxics10100576

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