The Vaccinia Virus DNA Helicase Structure from Combined Single-Particle Cryo-Electron Microscopy and AlphaFold2 Prediction

Poxviruses are large DNA viruses with a linear double-stranded DNA genome circularized at the extremities. The helicase-primase D5, composed of six identical 90 kDa subunits, is required for DNA replication. D5 consists of a primase fragment flexibly attached to the hexameric C-terminal polypeptide...

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Detalles Bibliográficos
Autores principales: Hutin, Stephanie, Ling, Wai Li, Tarbouriech, Nicolas, Schoehn, Guy, Grimm, Clemens, Fischer, Utz, Burmeister, Wim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611036/
https://www.ncbi.nlm.nih.gov/pubmed/36298761
http://dx.doi.org/10.3390/v14102206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611036/
https://www.ncbi.nlm.nih.gov/pubmed/36298761
http://dx.doi.org/10.3390/v14102206

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