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Intrinsic Aqueous Solubility: Mechanistically Transparent Data-Driven Modeling of Drug Substances

Intrinsic aqueous solubility is a foundational property for understanding the chemical, technological, pharmaceutical, and environmental behavior of drug substances. Despite years of solubility research, molecular structure-based prediction of the intrinsic aqueous solubility of drug substances is s...

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Detalles Bibliográficos
Autores principales: Oja, Mare, Sild, Sulev, Piir, Geven, Maran, Uko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611068/
https://www.ncbi.nlm.nih.gov/pubmed/36297685
http://dx.doi.org/10.3390/pharmaceutics14102248