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Simultaneous Determination of Glibenclamide and Silymarin Released from Chitosan Microparticles by HPLC-ESI-MS Technique: Method Development and Validation

The study aim was to develop and validate a high-performance liquid chromatography–electrospray ionization mass spectrometry (HPLC-ESI-MS) method to simultaneously determine glibenclamide (Gli) and silymarin (Sil) released from chitosan (CS) microparticles in aqueous solutions. The CS microparticles...

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Detalles Bibliográficos
Autores principales: Condurache, Mihaela-Iustina, Petrovici, Anca-Roxana, Simionescu, Natalia, Profire, Bianca-Stefania, Confederat, Luminita-Georgeta, Bujor, Alexandra, Miron, Anca, Profire, Lenuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611085/
https://www.ncbi.nlm.nih.gov/pubmed/36297600
http://dx.doi.org/10.3390/pharmaceutics14102164