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(+)-Usnic Acid and Its Derivatives as Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses

In order to test the antiviral activity, a series of usnic acid derivatives were synthesized, including new, previously undescribed compounds. The activity of the derivatives against three strains of SARS-CoV-2 virus was studied. To understand the mechanism of antiviral action, the inhibitory activi...

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Detalles Bibliográficos
Autores principales: Filimonov, Aleksandr S., Yarovaya, Olga I., Zaykovskaya, Anna V., Rudometova, Nadezda B., Shcherbakov, Dmitriy N., Chirkova, Varvara Yu., Baev, Dmitry S., Borisevich, Sophia S., Luzina, Olga A., Pyankov, Oleg V., Maksyutov, Rinat A., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611092/
https://www.ncbi.nlm.nih.gov/pubmed/36298709
http://dx.doi.org/10.3390/v14102154