Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells

The present study is to explore the anticancer effect of loonamycin (LM) in vitro and in vivo, and investigate the underlying mechanism with combined multi-omics. LM exhibited anticancer activity in human triple negative breast cancer cells by promoting cell apoptosis. LM administration inhibited th...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Lu, Zhanying, Liang, Zhenzhen, Deng, Bowen, Zhu, Yuping, Shi, Jing, Lu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611194/
https://www.ncbi.nlm.nih.gov/pubmed/36296549
http://dx.doi.org/10.3390/molecules27206958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611194/
https://www.ncbi.nlm.nih.gov/pubmed/36296549
http://dx.doi.org/10.3390/molecules27206958

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