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Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells
The present study is to explore the anticancer effect of loonamycin (LM) in vitro and in vivo, and investigate the underlying mechanism with combined multi-omics. LM exhibited anticancer activity in human triple negative breast cancer cells by promoting cell apoptosis. LM administration inhibited th...
Autores principales: | Sun, Xiao, Lu, Zhanying, Liang, Zhenzhen, Deng, Bowen, Zhu, Yuping, Shi, Jing, Lu, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611194/ https://www.ncbi.nlm.nih.gov/pubmed/36296549 http://dx.doi.org/10.3390/molecules27206958 |
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