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Design, Synthesis, Anticancer Activity and Molecular Docking of New 1,2,3-Triazole-Based Glycosides Bearing 1,3,4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds

New 1,3,4-thiadiazole thioglycosides linked to a substituted arylidine system were synthesized via heterocyclization via click 1,3-dipolar cycloaddition. The click strategy was used for the synthesis of new 1,3,4-thiadiazole and 1,2,3-triazole hybrid glycoside-based indolyl systems as novel hybrid m...

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Detalles Bibliográficos
Autores principales: Elganzory, Hussein H., Alminderej, Fahad M., El-Bayaa, Mohamed N., Awad, Hanem M., Nossier, Eman S., El-Sayed, Wael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611297/
https://www.ncbi.nlm.nih.gov/pubmed/36296551
http://dx.doi.org/10.3390/molecules27206960