The Use of the QbD Approach to Optimize the Co-Loading of Simvastatin and Doxorubicin in Liposomes for a Synergistic Anticancer Effect

The present study aimed to optimize a liposomal formulation co-encapsulating simvastatin (SIM) and doxorubicin (DOX) that has future perspectives in anticancer therapy. The optimization process was performed by implementing the Quality by Design concept and by considering the results of a previous s...

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Detalles Bibliográficos
Autores principales: Barbalata, Cristina-Ioana, Porfire, Alina Silvia, Casian, Tibor, Muntean, Dana, Rus, Iulia, Tertis, Mihaela, Cristea, Cecilia, Pop, Anca, Cherfan, Julien, Loghin, Felicia, Tomuta, Ioan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611314/
https://www.ncbi.nlm.nih.gov/pubmed/36297322
http://dx.doi.org/10.3390/ph15101211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611314/
https://www.ncbi.nlm.nih.gov/pubmed/36297322
http://dx.doi.org/10.3390/ph15101211

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