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Proposal to Consider Chemical/Physical Microenvironment as a New Therapeutic Off-Target Approach

The molecular revolution could lead drug discovery from chance observation to the rational design of new classes of drugs that could simultaneously be more effective and less toxic. Unfortunately, we are witnessing some failure in this sense, and the causes of the crisis involve a wide range of epis...

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Detalles Bibliográficos
Autores principales: Giuliani, Alessandro, Fais, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611316/
https://www.ncbi.nlm.nih.gov/pubmed/36297518
http://dx.doi.org/10.3390/pharmaceutics14102084