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Construction and Transcriptomic Study of Chicken IFNAR1-Knockout Cell Line Reveals the Essential Roles of Cell Growth- and Apoptosis-Related Pathways in Duck Tembusu Virus Infection

For industrial vaccine production, overwhelming the existing antiviral innate immune response dominated by type I interferons (IFN-I) in cells would be a key factor improving the effectiveness and production cost of vaccines. In this study, we report the construction of an IFN-I receptor 1 (IFNAR1)-...

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Detalles Bibliográficos
Autores principales: Xiang, Chengwei, Yang, Zekun, Xiong, Ting, Wang, Ting, Yang, Jie, Huang, Mei, Liu, Dingxiang, Chen, RuiAi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611459/
https://www.ncbi.nlm.nih.gov/pubmed/36298780
http://dx.doi.org/10.3390/v14102225