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Construction and Transcriptomic Study of Chicken IFNAR1-Knockout Cell Line Reveals the Essential Roles of Cell Growth- and Apoptosis-Related Pathways in Duck Tembusu Virus Infection
For industrial vaccine production, overwhelming the existing antiviral innate immune response dominated by type I interferons (IFN-I) in cells would be a key factor improving the effectiveness and production cost of vaccines. In this study, we report the construction of an IFN-I receptor 1 (IFNAR1)-...
Autores principales: | Xiang, Chengwei, Yang, Zekun, Xiong, Ting, Wang, Ting, Yang, Jie, Huang, Mei, Liu, Dingxiang, Chen, RuiAi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611459/ https://www.ncbi.nlm.nih.gov/pubmed/36298780 http://dx.doi.org/10.3390/v14102225 |
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