Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development

The primary objective of this study was to characterize the disease course in cynomolgus macaques exposed to Sudan virus (SUDV), to determine if infection in this species is an appropriate model for the evaluation of filovirus countermeasures under the FDA Animal Rule. Sudan virus causes Sudan virus...

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Detalles Bibliográficos
Autores principales: Alfson, Kendra J., Goez-Gazi, Yenny, Gazi, Michal, Chou, Ying-Liang, Niemuth, Nancy A., Mattix, Marc E., Staples, Hilary, Klaffke, Benjamin, Rodriguez, Gloria F., Escareno, Priscilla, Bartley, Carmen, Ticer, Anysha, Clemmons, Elizabeth A., Dutton III, John W., Griffiths, Anthony, Meister, Gabe T., Sanford, Daniel C., Cirimotich, Chris M., Carrion, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611481/
https://www.ncbi.nlm.nih.gov/pubmed/36298588
http://dx.doi.org/10.3390/vaccines10101723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611481/
https://www.ncbi.nlm.nih.gov/pubmed/36298588
http://dx.doi.org/10.3390/vaccines10101723

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