Optimization of Resveratrol Used as a Scaffold to Design Histone Deacetylase (HDAC-1 and HDAC-2) Inhibitors

Histone deacetylases (HDAC) are epigenetic enzymes responsible for repressing gene expression through the deacetylation of histone lysine residues. Therefore, inhibition of HDACs has become an interesting approach for the treatment of several diseases, including cancer, hematology, neurodegenerative...

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Detalles Bibliográficos
Autores principales: Urias, Beatriz Silva, Pavan, Aline Renata, Albuquerque, Gabriela Ribeiro, Prokopczyk, Igor Muccilo, Alves, Tânia Mara Ferreira, de Melo, Thais Regina Ferreira, Sartori, Geraldo Rodrigues, da Silva, João Hermínio Martins, Chin, Chung Man, Santos, Jean Leandro Dos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611521/
https://www.ncbi.nlm.nih.gov/pubmed/36297372
http://dx.doi.org/10.3390/ph15101260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611521/
https://www.ncbi.nlm.nih.gov/pubmed/36297372
http://dx.doi.org/10.3390/ph15101260

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