Estradiol, Estrone and Ethinyl Estradiol Metabolism Studied by High Resolution LC-MS/MS Using Stable Isotope Labeling and Trapping of Reactive Metabolites

Biotransformation reactions that xenobiotics undergo during their metabolism are crucial for their proper excretion from the body, but can also be a source of toxicity, especially in the case of reactive metabolite formation. Unstable, reactive metabolites are capable of covalent binding to proteins...

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Detalles Bibliográficos
Autores principales: Chabi, Kahina, Sleno, Lekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611524/
https://www.ncbi.nlm.nih.gov/pubmed/36295833
http://dx.doi.org/10.3390/metabo12100931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611524/
https://www.ncbi.nlm.nih.gov/pubmed/36295833
http://dx.doi.org/10.3390/metabo12100931

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