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The Bioactive Phenolic Agents Diaryl Ether CVB2-61 and Diarylheptanoid CVB4-57 as Connexin Hemichannel Blockers

Inflammation mediators enhance the activity of connexin (Cx) hemichannels, especially in the epithelial and endothelial tissues. As potential release routes for injury signals, such as (oligo)nucleotides, Cx hemichannels may contribute to long-lasting inflammation. Specific inhibition of Cx hemichan...

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Detalles Bibliográficos
Autores principales: Dierks, Anne, Vanucci-Bacqué, Corinne, Schäfer, Anne-Marie, Lehrich, Tina, Ruhe, Frederike, Schadzek, Patrik, Bedos-Belval, Florence, Ngezahayo, Anaclet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611528/
https://www.ncbi.nlm.nih.gov/pubmed/36297285
http://dx.doi.org/10.3390/ph15101173