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The Bioactive Phenolic Agents Diaryl Ether CVB2-61 and Diarylheptanoid CVB4-57 as Connexin Hemichannel Blockers
Inflammation mediators enhance the activity of connexin (Cx) hemichannels, especially in the epithelial and endothelial tissues. As potential release routes for injury signals, such as (oligo)nucleotides, Cx hemichannels may contribute to long-lasting inflammation. Specific inhibition of Cx hemichan...
Autores principales: | Dierks, Anne, Vanucci-Bacqué, Corinne, Schäfer, Anne-Marie, Lehrich, Tina, Ruhe, Frederike, Schadzek, Patrik, Bedos-Belval, Florence, Ngezahayo, Anaclet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611528/ https://www.ncbi.nlm.nih.gov/pubmed/36297285 http://dx.doi.org/10.3390/ph15101173 |
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