Chitosan Oligosaccharide Prevents Afatinib-Induced Barrier Disruption and Chloride Secretion through Modulation of AMPK, PI3K/AKT, and ERK Signaling in T84 Cells

Diarrhea is an important adverse effect of epidermal growth factor receptor-tyrosine kinase inhibitors, especially afatinib. Novel antidiarrheal agents are needed to reduce epidermal growth factor receptor-tyrosine kinase inhibitor-associated diarrhea to improve the quality of life and treatment out...

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Detalles Bibliográficos
Autores principales: Mehmood, Tahir, Pichyangkura, Rath, Muanprasat, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611671/
https://www.ncbi.nlm.nih.gov/pubmed/36297833
http://dx.doi.org/10.3390/polym14204255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611671/
https://www.ncbi.nlm.nih.gov/pubmed/36297833
http://dx.doi.org/10.3390/polym14204255

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