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Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV Infection

In this study, we evaluate the role of the MIF/CD74 axis in the functionality of CD4(+) T lymphocytes (CD4TL) during HIV infection. MDMs from healthy donors were infected with a R5-tropic or Transmitted/Founder (T/F) HIV strain. At day 11 post-MDM infection, allogeneic co-cultures with uninfected CD...

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Detalles Bibliográficos
Autores principales: Trifone, César, Baquero, Lucía, Czernikier, Alejandro, Benencio, Paula, Leng, Lin, Laufer, Natalia, Quiroga, María Florencia, Bucala, Richard, Ghiglione, Yanina, Turk, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611675/
https://www.ncbi.nlm.nih.gov/pubmed/36298774
http://dx.doi.org/10.3390/v14102218