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Sticker-and-spacer model for amyloid beta condensation and fibrillation

A major pathogenic hallmark of Alzheimer's disease is the presence of neurotoxic plaques composed of amyloid beta (Aβ) peptides in patients' brains. The pathway of plaque formation remains elusive, though some clues appear to lie in the dominant presence of Aβ(1 − 42) in these plaques desp...

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Detalles Bibliográficos
Autores principales: Connor, Jack P., Quinn, Steven D., Schaefer, Charley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611774/
https://www.ncbi.nlm.nih.gov/pubmed/36311031
http://dx.doi.org/10.3389/fnmol.2022.962526