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The Novel hDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis

The pharmacological management of influenza virus (IV) infections still poses a series of challenges due to the limited anti-IV drug arsenal. Therefore, the development of new anti-influenza agents effective against antigenically different IVs is therefore an urgent priority. To meet this need, host...

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Detalles Bibliográficos
Autores principales: Sibille, Giulia, Luganini, Anna, Sainas, Stefano, Boschi, Donatella, Lolli, Marco Lucio, Gribaudo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611833/
https://www.ncbi.nlm.nih.gov/pubmed/36298835
http://dx.doi.org/10.3390/v14102281