Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling

Cisplatin (CIS) is an effective chemotherapeutic agent against different cancers. The use of CIS is associated with acute lung injury (ALI) and other adverse effects, and oxidative stress and inflammation were implicated in its toxic effects. Candesartan (CAN), an angiotensin II (Ang II) receptor bl...

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Detalles Bibliográficos
Autores principales: Atwa, Ahmed M., Abd El-Ghafar, Omnia A. M., Hassanein, Emad H. M., Mahdi, Somya E., Sayed, Ghadir A., Alruhaimi, Reem S., Alqhtani, Haifa A., Alotaibi, Mohammed F., Mahmoud, Ayman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612036/
https://www.ncbi.nlm.nih.gov/pubmed/36297334
http://dx.doi.org/10.3390/ph15101222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612036/
https://www.ncbi.nlm.nih.gov/pubmed/36297334
http://dx.doi.org/10.3390/ph15101222

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