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Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling
Cisplatin (CIS) is an effective chemotherapeutic agent against different cancers. The use of CIS is associated with acute lung injury (ALI) and other adverse effects, and oxidative stress and inflammation were implicated in its toxic effects. Candesartan (CAN), an angiotensin II (Ang II) receptor bl...
Autores principales: | Atwa, Ahmed M., Abd El-Ghafar, Omnia A. M., Hassanein, Emad H. M., Mahdi, Somya E., Sayed, Ghadir A., Alruhaimi, Reem S., Alqhtani, Haifa A., Alotaibi, Mohammed F., Mahmoud, Ayman M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612036/ https://www.ncbi.nlm.nih.gov/pubmed/36297334 http://dx.doi.org/10.3390/ph15101222 |
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