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Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity

Immune cell state alterations rewire HIV-1 gene expression, thereby influencing viral latency and reactivation, but the mechanisms are still unfolding. Here, using a screen approach on CD4(+) T cell models of HIV-1 latency, we revealed Small Molecule Reactivators (SMOREs) with unique chemistries alt...

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Detalles Bibliográficos
Autores principales:	Cruz-Lorenzo, Emily, Ramirez, Nora-Guadalupe P., Lee, Jeon, Pandhe, Sonali, Wang, Lei, Hernandez-Doria, Juan, Spivak, Adam M., Planelles, Vicente, Petersen, Tianna, Jain, Mamta K., Martinez, Elisabeth D., D’Orso, Iván
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612055/ https://www.ncbi.nlm.nih.gov/pubmed/36298843 http://dx.doi.org/10.3390/v14102288

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