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Quantum Chemical Computation of Omicron Mutations Near Cleavage Sites of the Spike Protein

The attachment of the spike protein in SARS-CoV-2 to host cells and the initiation of viral invasion are two critical processes in the viral infection and transmission in which the presence of unique furin (S1/S2) and TMPRSS2 (S2′) cleavage sites play a pivotal role. We provide a detailed analysis o...

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Detalles Bibliográficos
Autores principales: Adhikari, Puja, Jawad, Bahaa, Podgornik, Rudolf, Ching, Wai-Yim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612061/
https://www.ncbi.nlm.nih.gov/pubmed/36296275
http://dx.doi.org/10.3390/microorganisms10101999