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Determining the temporal, dose, and composition effects of nutritional substrates in an in vitro model of intrahepatocellular triglyceride accumulation

Pathological accumulation of intrahepatic triglyceride underpins the early stages of nonalcoholic fatty liver disease (NAFLD) and can progress to fibrosis, cirrhosis, and cancer of the liver. Studies in humans suggest that consumption of a diet enriched in saturated compared to unsaturated fatty aci...

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Detalles Bibliográficos
Autores principales: Nagarajan, Shilpa R., Cross, Eloise, Johnson, Elspeth, Sanna, Fabio, Daniels, Lorna J., Ray, David W., Hodson, Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612139/
https://www.ncbi.nlm.nih.gov/pubmed/36301719
http://dx.doi.org/10.14814/phy2.15463